IMPACT OF EDUCATIONAL INTERVENTION ON KNOWLEDGE, ATTITUDE AND PRACTICE OF PHARMACOVIGILANCE AMONG MEDICAL GRADUATES OF RURAL TERTIARY CARE, TEACHING HOSPITAL OF CENTRAL INDIA

  • Satish Bahekar Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
  • Shailesh Nagpure Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
  • Ranjana Kale Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
  • Sushil Kumar Varma Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India

Abstract

Objectives: To assess the awareness of Pharmacovigilance among the medical graduates and to evaluate the need of inclusion of KAP (Knowledge, Attitude and Practice) of Pharmacovigilance in Internship Training Programme as an educational intervention.Material and Methods: The present study was conducted in the Internship orientation program in a rural hospital of central India. It was a Hospital Based Cross Sectional Study in which 65 Interns (medical graduates) were participated. Semi-structured, Pre-Designed, Pre-tested Questionnaire was used for data collection. Data was entered and analyzed using statistical software ‘EPI INFO 3.5.3’.Results: In our study a total of 65 medical graduates were responded and involved in the pre KAP and post KAP survey questionnaires. The overall response rate between pre intervention and post intervention was statistically significant and that shows effectiveness of educational intervention for improving awareness of Pharmacovigilance among medical graduates.Conclusion: Imparting the knowledge and awareness of Pharmacovigilance among the medical graduates by mean of continuous educational intervention would bring update of knowledge for drug safety into their everyday clinical practice and also bring the adverse drug reactions(ADRs) reporting culture among them.

Author Biographies

Satish Bahekar, Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Shailesh Nagpure, Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Ranjana Kale, Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Sushil Kumar Varma, Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India
Department of Pharmacology, Mahatma Gandhi Institute of Medical Sciences,Sewagram, Wardha,Maharashtra 442102, India

References

Von Laue NC, Schwappach DL, Koeck CM. The epidemiology of preven Figure adverse drug events: a review of literature. Wien Klin Wochenschr. 2003 July 15;115(12):407-15.

Wu WK, Pantaleo N. Evaluation of outpatient adverse drug reactions leading to hospitalization. Am J Health Syst Pharm. 2003 February 1;60(3):253-9.

Lazarou J, Pomeranz BH, Corey PN: Incidence of adverse reactions in hospitalized patients. A metaanalysis of prospective studies. JAMA. 1998;279:1200-05.

Pirmohamed M, James S, Meakin S, Green C, Scott AK, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients. Br Med J. 2004;329:15-19.

Oshikoya KA. Adverse drug reaction in children: types, incidence and risk factors. Nig J Paediatr. 2006;33:29-35.

Martinez-Mir I, Garcia-Lopez M, Palop V, Ferrer JM, Rubio E, Morales- Olivas FJ: A prospective study of adverse drug reactions in hospitalized children. Br J Clin Pharmacol. 1999;47:681-8.

Ahmad SR. Adverse drug event monitoring at the Food and Drug Administration. J Gen Intern Med. 2003;18:57-60.

Wysowski DK, Swartz L. Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: the importance of reporting suspected reactions. Arch Intern Med. 2005; 165:1363-69.

Hazell L, Shakir SA. Under-reporting of adverse drug reactions: a systematic review. Drug Saf. 2006;29:385-96.

Moride Y, Haramburu F, Requejo AA, Begaud B. Under-reporting of adverse drug reactions in general practice. Br J Clin Pharmacol. 1997;43:177-81.

Heeley E, Riley J, Layton D, Wilton LV, Shakir SAW. Prescription-event monitoring and reporting of adverse drug reactions. Lancet. 2001;358:1872-3.

Figueiras A, Tato F, Fontainas J, Gestal-Otero JJ.Influence of physicians’ attitudes on reporting adverse drug events: a case-control study. Med Care. 1999;37:809-14.

Williams D, Feely J. Underreporting of adverse drug reactions: attitudes of Irish doctors. Ir J Med Sci. 1999;168:257-61.

Perlik F, Slanar O, Smid M, Petracek J. Attitude of Czech physicians to adverse drug reaction reporting. Eur J Clin Pharmacol. 2002;58:367-69.

Belton KJ, Lewis SC, Payne S, Rawlins MD. Attitudinal survey of adverse drug reaction reporting by medical practitioners in the United Kingdom. Br J Clin Pharmacol. 1995; 39:223-26.

Hasford J, Goettler M, Munter KH, Muller- Oerlinghausen B. Physicians’ knowledge and attitudes regarding the spontaneous reporting system for adverse drug reactions. J Clin Epidemiol. 2002;55:945-50.

Herdeiro MT, Figueiras A, Polo´ nia J, Gestal- Otero JJ. Physicians’ attitudes and adverse drug reaction reporting: a case-control study in Portugal. Drug Saf. 2005; 28:825-33.

Rajesh R, Vidyasagar S, Nandakumar K. Highly active antiretroviral therapy induced adverse drug reactions in Indian human immunodeficiency virus positive patients. Pharmacy Practice. 2011 Jan- Mar;9(1):48-55.

Radhakrishnan R, Vidyasagar S, Varma DM. An Educational Intervention to assess Knowledge Attitude Practice of pharmacovigilance among Health care professionals in an Indian tertiary care teaching hospital. Int.J. PharmTech Res. 2011;3(2):678-92.

Wallace SM, Suveges LG, Gesy KF. Adverse drug reaction reporting part I: a survey of pharmacists and physicians in Saskatchewan. Drug Information Journal. 1995;29:571-79.

Suveges LG, Gesy KF, Wallace SM, Blackburn JL, Appel WC. Adverse drug reaction reporting part II: evaluation of the Saskatchewan pilot project for a regional reporting program in Canada. Drug Information Journal. 1995;29:581-89.

Scolt HD, Thacher – Renshaw A, Rosenbaum SE, Waters WJ, Green M, Andrews LG et al. Physician reporting of adverse drug reactions: results of the Rhode Island adverse drug reaction reporting project. JAMA. 1990;263:1785-88.

Cosentino M, Leoni O, Banfi F, Lecchini S, Frigo G: Attitudes to adverse drug reaction reporting by medical practitioners in a Northern Italian district. Pharmacol Res. 1997;35:85-8.

Figueiras A, Herdeiro MT, Polonia J, Gestal-Otero JJ: An educational intervention to improve physician reporting of adverse drug reactions: a cluster-randomized controlled trial. JAMA. 2006;296:1086-93.

Ramesh M, Parthasarathi G. Adverse Drug Reactions Reporting: Attitudes and Perceptions of Medical Practitioners. Asian J of Pharmaceutical and Clinical Research. 2009;2:10-14.

Lopez-Gonzalez E, Herdeiro MT, Figueiras A: Determinants of under-reporting of adverse drug reactions: a systematic review. Drug Saf. 2009;32:19-31.

Eland IA, Belton KJ, van Grootheest AC, Meiners AP, Rawlins MD, Stricker BH: Attitudinal survey of voluntary reporting of adverse drug reactions. Br J Clin Pharmacol. 1999;48:623-7.

Hasford J, Goettler M, Munter KH, Muller- Oerlinghausen B: Physicians' knowledge and attitudes regarding the spontaneous reporting system for adverse drug reactions. J Clin Epidemiol. 2002;55:945-50.

Chatterjee S, Lyle N, Ghosh S: A survey of the knowledge, attitude and practice of adverse drug reaction reporting by clinicians in eastern India. Drug Saf. 2006;29(7):641-2

Published
2013-04-01
How to Cite
Bahekar, S., Nagpure, S., Kale, R., & Varma, S. K. (2013). IMPACT OF EDUCATIONAL INTERVENTION ON KNOWLEDGE, ATTITUDE AND PRACTICE OF PHARMACOVIGILANCE AMONG MEDICAL GRADUATES OF RURAL TERTIARY CARE, TEACHING HOSPITAL OF CENTRAL INDIA. Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315), 51-54. Retrieved from http://mjpms.in/index.php/mjpms/article/view/107