RECENT ADVANCES IN GASTRO RETENTIVE DRUG DELIVERY SYSTEM: A REVIEW

  • Jhansee Mishra Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001
  • Alok Kumar Dash Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001

Abstract

Several controlled oral drug delivery systems with prolonged gastric residence time have been reported recently. Gastro retentive drug delivery system is an approach to prolong gastric residence time, thereby targeting site-specific drug release in upper gastro intestinal tract improving the oral sustained delivery of drug that have an absorption window in a particular region of the gastrointestinal tract. These systems help in continuously releasing the drug before it reaches the absorption window, thus ensuring optimal bioavailability. Various approaches for gastric retention are Floating system, Swelling and expanding system, Bioadhesive systems, Modified-shape systems, High density systems etc.

Author Biographies

Jhansee Mishra, Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001
Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001 
Alok Kumar Dash, Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001
Assistant Professor Department of Pharmacy, V.B.S.purvanchaluniversity, jaunpur,U.P, India ,222001

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Published
2013-04-01
How to Cite
Mishra, J., & Dash, A. K. (2013). RECENT ADVANCES IN GASTRO RETENTIVE DRUG DELIVERY SYSTEM: A REVIEW. Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315), 25-27. Retrieved from http://mjpms.in/index.php/mjpms/article/view/115