A GLANCE ON PHARMACOGENOMICS BASIS ON GENETIC DISORDERS AND ADVANCES IN RECOMBINANT-DNA TECHNOLOGY AS A NEW APPROACH

  • Krishna Ravi Dr. Krishna Ravi Lecturer, Department of pharmacy practice Contact number: +8301828295 Mail.id : drkrishnaravi.7kr@gmail.com JKK Nattraja college of pharmacy. Komarapalyam. Tamilnadu
  • Sudha M Assistant Professor, Department of pharmacology, JKK Nattraja College of pharmacy, Komarapalyam.
  • Venkateswarmurthy N Professor, Department of pharmacy practice JKK Nattraja college of pharmacy
  • Sambathkumar R Principal& Professor, Department of pharmaceutics, JKK Nattraja College of pharmacy, Komarapalyam.

Abstract

Background: Advent of r-DNA techniques and their application to biology and healthcare system is one of the most exciting eras of scientific history. Objectives: In this review, we discuss about pharmacogenetics, pharmacogenomics, advances, applications, challenges and future perspectives of r-DNA technology. Variability in drug responses is the net result of multiple interacting genes and environmental factors. Conclusion: We found that many technical and conceptual barriers still remain unveil to the world, if the true potential of this field recognize, the genetic disorders will completely disappear and will get a solution for most questionable microbial resistance. It is anticipated that less than 10% of drugs in 10 years from now will be prescribed following a pharmacogenetic test. In future, we need more intensive studies in the areas of pharmacogenomics to identify the targeted gene which is responsible for specific diseases or variable drug response, so the r-DNA technology can easily develop a new drug molecule which can change the gene expression or may modify the targeted gene. Field of pharmacogenomics will lead to new important insights and discoveries that will ultimately lead to the development of new and better drugs and to the rational use of drugs that are already on the market.

Key words:  r-DNA, pharmacogenetics, pharmacogenomics, genetic disorders, gene expression.

Author Biographies

Krishna Ravi, Dr. Krishna Ravi Lecturer, Department of pharmacy practice Contact number: +8301828295 Mail.id : drkrishnaravi.7kr@gmail.com JKK Nattraja college of pharmacy. Komarapalyam. Tamilnadu
Lecturer, department of pharmacy practice JKK Nattraja college of pharmacy komarapalaym, Tamilnadu
Sudha M, Assistant Professor, Department of pharmacology, JKK Nattraja College of pharmacy, Komarapalyam.

Assistant Professor, Department of pharmacology,

JKK Nattraja College of pharmacy, Komarapalyam.

+8883109254

Venkateswarmurthy N, Professor, Department of pharmacy practice JKK Nattraja college of pharmacy

Professor, Department of pharmacy practice

JKK Nattraja college of pharmacy

Sambathkumar R, Principal& Professor, Department of pharmaceutics, JKK Nattraja College of pharmacy, Komarapalyam.

Principal& Professor, Department of pharmaceutics,

            JKK Nattraja College of pharmacy, Komarapalyam.

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Published
2018-10-01
How to Cite
Ravi, K., M, S., N, V., & R, S. (2018). A GLANCE ON PHARMACOGENOMICS BASIS ON GENETIC DISORDERS AND ADVANCES IN RECOMBINANT-DNA TECHNOLOGY AS A NEW APPROACH. Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315), 1-6. Retrieved from http://mjpms.in/index.php/mjpms/article/view/399