ERYTHRINA VARIEGATA LINN: A REVIEW ON PHYTOCHEMISTRY, PHARMACOLOGICAL CHARACTERISTIC
Background: Erythrina variegata plant has properties to cure various diseases including effective as antidiabetic, cardiac depressant, anticovulsant, antimalarial, analgesic and anti-inflammatory. Erythrina Variegata contains alkaloids, flavonoids, triterpenoids and lectins. As well as containing the compounds of the isoflavone derivative Genistein which can prevent osteoporosis. The new isoflavonoid compounds, namely Eryvarins V, W and X from the extract of E. variegata root as a potential antibacterial. Ethanol extract of leaves and E. variegata water fraction with a concentration of 10% can significantly nourish hair. This article covers phytochemical aspects and pharmacological characteristics of the E. variegate plant as an attempt to further research. Conclusions: From the results of the research pharmacologically, compounds that are effective as anti-alopecia have not been found so it is necessary to identify compounds in Erythrina variegata which are effective as anti-alopecia.
Keyword: Erythrina Variegata, Antialopecia, Fabaceae
Vanlalremkimi, Lalnundanga J, Khanduri V and Kewat S. Phenological Patterns of Erythrina Variegata and Erythrina Subumbrans in Two Distinct Precipitation Regime in Tropical Forests of Mizoram, Ne-India. International Journal of Agriculture Sciences. 2016; 8: 1736-1740.
Yusuf U.K. Erythrina subumbrans (Hassk.) Merr. In: Faridah Hanum, I & van der Maesen, L.J.G, editors. Plant Resources of South-East Asia No. 11. Auxiliary Plants. Prosea Foundation, Bogor, Indonesia; 1997. p. 126-128.
Stefani Tjiphanata, Edwin De Queljoe and Sri Sudewi. Pengaruh Pemberian Ekstrak Etanol Daun Dadap Ayam (Erythrina variegate L) Terhadap Kualitas Spermatozoa Tikus Putih Jantan Galur Wistar (Rattus Norvegicus). Pharmacon Jurnal Ilmiah Farmasi. 2017; 6: 2302-2493.
Murugalakshmi M, Mari S and Thangapandian V. Analgesic and Anti-Inflammatory Activities of Erythrina Variegata Leaves Extracts. J. of Advanced Botany and Zoology. 2014; 2: 2348 â€“ 7313.
Devaki K, Priyanga S and Hemmalakshmi S. Antidiabetic activity of aqueous extract of Erythrina variegata L.bark in streptozotocin induced diabetic rats. Journal of Chemical and Pharmaceutical Research. 2016; 8: 306-312.
Kumar Arvind, Lingadurai Sutharson, Shrivastava Tarani P, Bhattacharya Sanjib, Haldar and Pallab K. Hypoglycemic activity of Erythrina variegata leaf in streptozotocin induced diabetic rats. Pharmaceutical Biology. 2011; 49: 577â€“582.
Karthikeyan R and Koushik OS. Cardiac Depressant Activity of Erythrina variegata Linn on Isolated Frog Heart. J Pharmacogn Nat Prod. 2015; 1: 107.
PT Sangale, DB Deshmukh and R Bhambere. Anticonvulsant Effect of Leaf and Bark of Erythrina Variegata Linn and Butea Monosperma (LAM) Taub in different Experimental Convulsion Model in Rats. PharmaTutor. 2015; 3: 19-23.
Zhang Yan, Li Qi, Li Xiaoli, Wan Hoi-Ying and Wong Man-Sau. Erythrina variegata extract exerts osteoprotective effects by suppression of the process of bone resorption. British Journal of Nutrition. 2010; 104: 965â€“ 971.
Herlina Tati, Julaeha Euis, Nurlelasari, Kurnia Dikdik and Supratman Unang. Potential of Dadap Ayam (Erythrina variegata) Plant as Herbal Medicine. Jurnal Medika Planta. 2011; 1: 40-48.
Herlina Tati, Supratman Unang, Urbanas Anas, Sutardjo Supriyatna, Abdullah Noor Rain and Hayashi Hideo. Triterpenoid Pentacyclic Antimalarial Activity from the Leaves of Erythrina variegate. Jurnal Ilmu Dasar. 2011; 12: 161 â€“ 166.
Tanaka Hitoshi, Atsumia Ikunori, Shirotab Osamu, Sekitab Setsuko, Sakaic Eiji, Satod Masaru, Muratae Jin, Murataf Hiroko, Darnaedig Dedy and Chenh Ih-Sheng. Three New Constituents from the Roots of Erythrina variegata and Their Antibacterial Activity against Methicillin-Resistant Staphylococcus aureus. Chemistry & Biodiversity. (2011); 8: 476-482.
Sato M, Tanaka H, Fujiwara S, Hirata M, Yamaguchi R, Etoh H and Tokuda C. Antibacterial property of isoflavonoids isolated from Erythrina variegata against cariogenic oral bacteria. Phytomedicine. 2003; 10: 427- 433.
Zhang Chao, Zhou Yuanming, Sun Zhenling, Feng Jing and Wang Yingzi. Polysaccharides extraction from Erythirna variegata, chemicalcharacterization and its antioxidant activity. International Journal of Biological Macromolecules. 2014; 68: 267- 273.
Liu Qi, Yu Jingang, Liao Xiaoyun, Zhang Peisen and Chen Xiaoqing. One-Step Separation of Antioxidant Compounds from Erythrina variegata by High Speed Counter-Current Chromatography. Journal of Chromatographic Science. 2015; 53: 730â€“735.
Mustarichie Resmi, Wicaksono Imam Adi and Gozali Dolih. Anti-Alopecia Activity of DADAP (Erythrina variegata L.) Leaves Ethanol Extract. Sci. & Res. 2017; 9: 1849-1854.
Shahnaz Sultana, Mohammed Ali and Showlat Rassol Mir. Chemical consistituents from the leaves of Adenanthera pavonina and Erythrina variegate and roots of Heliotropium eichwaldii. International Journal of Advances in Pharmacy Medicine and Bioallied Sciences. 2017; 5: 217-224.
Muthukrishnan Suriyavathana, Palanisamy Subha, Subramanian Senthilkumar, Selvaraj Sumathi, Maril Kavitha Rani and Kuppulingam Ramalingam. Phytochemical Profile of Erythrina variegata by Using High-Performance Liquid Chromatography and Gas Chromatography-Mass Spectroscopy Analyses. Journal of Acupuncture and Meridian Studies. 2016; 9: 207-212.
Tanaka Hitoshi, Hirata Miyuki, Etohb Hideo, Shimizuc Hiroshi, Sakod Magoichi, Muratae Jin, Murataf Hiroko, Darnaedig Dedy and Fukaih Toshio. Eryvarins F and G, two 3-phenoxychromones from the roots of Erythrina variegate, Phytochemistry. 2003; 62: 1243â€“1246.
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