INVESTIGATION OF ANTIOXIDANT ACTIVITY OF HYDROALCOHOLIC LEAF EXTRACT OF CUCUMIS MELO VAR AGRESTIS (CUCURBITACEAE) - A WILD EDIBLE PLANT FROM INDIA

Antioxidant activity of Cucumis melo var agrestis

  • Gopalasatheeskumar K Department of Pharmacology, KMCH college of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore-641048, Tamil Nadu, India(Affiliated to The Tamil Nadu Dr. M.G.R. Medical University).
  • Ariharasivakumar G Professor and Head of the Department of Pharmacology, KMCH college of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore-641048, Tamil Nadu, India (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University).
  • Sengottuvel T Associate Professor, Department of Pharmacology, KMCH college of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore-641048, Tamil Nadu, India (Affiliated to The Tamil Nadu Dr. M.G.R. Medical University).
  • Sanish Devan V Department of Pharmacology, KMCH college of Pharmacy, Kovai Estate, Kalapatti Road, Coimbatore-641048, Tamil Nadu, India(Affiliated to The Tamil Nadu Dr. M.G.R. Medical University).
Keywords: Total antioxidant capacity, Quercetin, Vitamin C, Mithukkuvathal sedi, Free radical

Abstract

Background: The antioxidants are important in life because the most of the diseases are caused by free radicals which are scavenged by the antioxidants. The antioxidants are prevents the oxidative stress of the cells. Natural products such as herbals and herbal extracts have reported as antioxidant property but there is no report on antioxidant properties of Cucumis melo var agrestis (CMA). Aim and Objectives: The present study is aimed to that evaluation of in vitro antioxidant activity of hydroalcoholic leaf extract of CMA (HALEC). Methods: The antioxidant activities were evaluated by DPPH assay, ABTS assay, FRAP assay and Phosphomolypdenum assay. Standard quercetin was used for the DPPH radical scavenging assay and ABTS radical scavenging assay and L-Ascorbic acid was used as a standard for FRAP assay and Phosphomolypdenum assay. Results: Our results revealed that HALEC has potent antidioxidant potential and it was compared with the standard quercetin and ascorbic acid. Conclusion: From the results of this research the HALEC has the potent antioxidant potential and further study needed to isolate the active principles.

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Published
2019-08-14
How to Cite
K, G., G, A., T, S., & V, S. D. (2019). INVESTIGATION OF ANTIOXIDANT ACTIVITY OF HYDROALCOHOLIC LEAF EXTRACT OF CUCUMIS MELO VAR AGRESTIS (CUCURBITACEAE) - A WILD EDIBLE PLANT FROM INDIA. Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315), 25-28. Retrieved from http://mjpms.in/index.php/mjpms/article/view/474
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Original Article(s)