Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315)

Author(s): DeyPrasanta &BhaktaTejendra

Methanolic extract of leaf of Musa acuminate colla and seed of Cajanus cajan (Linn.) were taken for the examination of anthelmintic activity on Indian earthworm (Pheretimaposthuma). Various concentrations (10mg/ml, 20mg/ml, 30 mg/ml) of both plant extract were tested and results were expressed in terms of time of paralysis and time of death of  worms.  Albendazole  of  same  concentration  as  like  as  plant  extracts  was  taken  as  reference  standard  and  normal  saline  solution  as  control.  Paralysis  time  can  be determined  by  vigorous  shaking  when  no  movement  wasobserved.  When  whitish  substances  were  secreted  from  the  body  that  one  was  termed  as  death  time.  Both  the extracts show significant anthelmintic activity but among these two Musa acuminate colla showed more anthelmintic activity than Cajanus cajan (Linn.). Future scope involves isolation of active constituents responsible for this action.