Mintage Journal of Pharmaceutical and Medical Sciences (ISSN: 2320-3315)

Author(s): NOOR AL-HUDA ALI A. H. SAEED, LIQAA JAMEEL IBRAHEEM, ISRAA M.S. AL-KADMY, HEBBA F. DELI AL-LAMI, SARA N. AZIZ

Objective: The effect of aqueous extract of Glycine max (soybean) in the structure of ovary was studied for the females of rats histologically. Methods: The total number of (60) white rats were involved in the present study, divided into three groups that treated as follows: the first group is the control group that have got the regular water and food, whereas, the second and third group were treated with the aqueous extract glycin max of concentration 3mg/ml for a period of two weeks and 4 weeks respectively. Results: The histological study for the aqueous glycin max extract treated groups showed no mortality or toxicologically clinical changes were observed through the experimental period. It also showed inhibition formation of primary and secondary with the primordial formation of follicales at 2 weeks and diffuse lutinization of the stroma of ovary with no follicales formation and presence of interstitial haemorrhage at 4 weeks. Comparing with the control group that showed the different stage of development of graafian luteum which reflects the effect of glycin max on the ovary activity.conclusions: The results of this study indicate the ability of the glycin max to inhibit the activity of ovary.